CNCB - Tool Info

Home/ Computational Analysis Tools/ McAN

Name	McAN
Type	Phylogeny and Molecular Evolution
Version	V1.4.1
Developers	Lun Li, Bo Xu, Anke Wang, Junwei Zhu
Description	McAN is a tool for constructing haplotype network based on minimum-cost arborescence. McAN overcomes the problems of slow processing speed and large memory consumption in traditional haplotype network construction algorithms, thereby enabling the evolutionary tracking analysis of massive SARS-CoV-2 sequences. Tests on a small dataset of around 1000 SARS-CoV-2 whole-genome data show that McAN runs two orders of magnitude faster than traditional methods. Tests on a large dataset of around 5 million SARS-CoV-2 sequences indicate that McAN can handle massive pathogenic genomic sequence data in about 25 minutes (with 50 threads). On test datasets, McAN has achieved accurate results while reducing memory consumption by over 90% compared with traditional methods. Moreover, McAN has demonstrated reasonable results on various datasets, including monkeypox and influenza A.
Downlaod	https://ngdc.cncb.ac.cn/biocode/tools/BT007301
Online Link	https://ngdc.cncb.ac.cn/bit/hapnet/
Article	https://doi.org/10.1093/bib/bbad174
Figure

1 Beichen West Road, Chaoyang District Beijing 100101, China | 86-10-84097216